Examination and clinical correlation of olfactory system disorders by an objective method Sniffin' Sticks odor test in Parkinson's disease

Objectives: This study is aimed to investigate the frequency of olfactory dysfunction in Parkinson’s Disease (PD) and its relationship with motor/non-motor symptoms treatment comparison isolated patients healthy controls.Methods: includes 40 PD patients, 37 anosmia 42 controls. are evaluated evaluation form including; sociodemographic features, disease history, Unified Rating Scale (UPDRS) score, Hoehn Yahr (H-Y) score. All were cranial CT MRI. Olfactory function was Sniffin' Sticks Test (SST). A p value < 0.05 considered be statistically significant. Results::The mean age median duration 62.2 ± 11.9 4.5 years, respectively. Fifteen them had comorbid diseases. Median UPDRS score 19.5 (4-60) 67.5% subjects H-Y Stage-1. Most frequent non-motor symptom constipation (67.5%). found 75% by SST. No difference observed between or without regarding dementia (p > 0.05). Patients significntly younger than both controls <0.001). Non-motor not significantly different group ?Conclusions: dysfunction, which correlated stage based on results an objective test, namely Sniffin-Sticks odor test.This result might support role non-dopaminergic pathways etiopathogenesis dysfunctions PD. In clinical practice, data from further studies required comment ideal screening diagnostic test system early that would repeatable objective.